GTA 2 with mouse aim is bliss! The controls could use to be a bit tighter, maybe, but it's already quite fun.
Replacing the merciless hearts-and-limited-respawns mechanic with something more modern also helps.
Also, advances in technology now allow us to beat people to death. However, advances in societal norms will make passers-by comment on you spamming "X" to fart and burp.
I just wish there was fancy laser sight aiming in this game.